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The What and How of the KBMD Health SIBO Support Box

This KBMD Health SIBO Support Box is the result of years of Research & Development in a complex field.  Here is a brief explanation of What the ingredients are, and How they work to relieve your SIBO symptoms.  Each Box contains 4 primary ingredients pre-portioned in easy-to-use AM and PM packets.


The first ingredient in both the AM and PM packet is Atrantil®

Atrantil® is the only patented polyphenol blend in the world that has been shown in clinical trials to help 4 out of 5 people address their symptoms of bloating, abdominal pain, and change in bowel habits.

Atrantil® is composed of three powerful natural polyphenols, that help get rid of the gas and the problematic bacteria in the small intestine. When your microbiome uses the Atrantil® as fuel, it produces beneficial molecules that have potent anti-cancer, anti-aging, and anti-inflammatory benefits throughout your entire body.


The second ingredient in the AM packet ONLY is Diamine Oxidase (DAO)

Diamine Oxidase is an enzyme produced by the lining of your digestive tract to help control the amount of histamine that gets absorbed in your body. Diamine Oxidase is also known as DAO for short.

Histamine is a compound that is involved in digestion and supports the nervous system and the immune system. When histamine levels get too high, it can disrupt all three of these systems.

The DAO in our formula is an easy-to-swallow, high-potency gastro-resistant mini-tablet, which is essential for releasing DAO in the small intestine, where it breaks down both foods and histamine produced by SIBO bacteria.

Anytime you eat anything with more histamine than your body can neutralize, it will get absorbed into your body leading to excess histamine. When this excess histamine is absorbed, it can cause issues like abdominal pain, cramps, diarrhea, constipation, and can also cause brain fog, fatigue, anxiety, and even migraines.

Some of the more common foods that have a high histamine are avocados, spinach, fermented foods, cheese, alcohol, and smoked meats, just to name a few.

There are many medications which decrease DAO: aspirin, ibuprofen, blood pressure medications, and anti-depressants. When you combine Atrantil with a high-quality DAO, like the one we are using, it makes a huge difference in what you can eat, and significantly reduces the effects of too much histamine.


The third ingredient in both the AM and PM packet is IgY Immunoglobulin

Immunoglobulin is known as an antibody. The most common is bovine IgG.  I use IgY because it is more effective than IgG; due to its shape, IgY can resist the digestive process and remain intact in the gut to get rid of bacteria, viruses, and allergens.

If you have SIBO you may experience “leaky gut”, where small bacterial particles and allergens leak through the tight junctions in the gut and ignite the immune response resulting in inflammation.

These small bacterial particles are called lipopolysaccharides or LPS. LPS is now considered one of the major causes of dementia and autoimmune disease.

IgY is known to tightly bind to LPS and remove it from the small bowel so that it can’t leak through the tight junctions and cause inflammation. Inflammation always indicates that the body is in distress.

Think of IgY like a bulldozer that removes SIBO debris: LPS, bacterial pieces, viruses, and food allergens. It moves that debris down into the colon where it then passes out of your body.


The final ingredient in the PM packet ONLY is OptiMag® 125

The addition of this specific Magnesium in the SIBO Support Box is because it contains Albion®’s TRAACS® lysinate glycinate (mineral amino acid chelate) and Albion’s chelated dimagnesium malate—both formulated for enhanced absorption.  This combination increases intestinal motility in the small bowel which we know plays a significate role in over 300 metabolic processes.

Magnesium has also been shown to decrease anxiety and help improve the quality of sleep in those with and without insomnia. This is extremely important because if you have anxiety, it can cause intestinal motility issues which results in persistent SIBO and more inflammation.


Atrantil® in the AM and PM packets comes in with its stable polyphenols and begins to soak up the gas and get rid of the bacteria that is growing in your small bowel (SIBO).

SIBO causes your DAO enzyme to be decreased, which then results in too much histamine being absorbed. The DAO supplement, in the AM packet only, neutralizes this excess histamine and prevents it from being absorbed.

Then the IgY Immunoglobulin supplement in the AM and PM packets works like a bulldozer doing cleanup. It removes all the bacteria, viruses, allergens and most importantly, Lipopolysaccharides (LPS: large molecules consisting of a lipid and a polysaccharide that are bacterial toxins).

Finally, the PM packet has a combination of three highly effective ingredients: Atrantil, IgY Immunoglobulin, and a superior magnesium which has been shown to increase intestinal motility, help support multiple metabolic processes, plus decrease anxiety while improving sleep.

The combination of these four high quality natural ingredients work together in specific ways to help your body recalibrate itself to address SIBO symptoms.  During the recalibration period you may experience physical changes and some discomfort; be patient with the process to achieve positive results.

A Simple SIBO Plan

This easy to follow 3-Month program addresses the root causes of SIBO (Small Intestinal Bacterial Overgrowth) to help recalibrate the foundation of your digestive system in the first 30 days. After recalibrating your microbiome your body will go into a 30-day Recovery period.  Your GI system will be working better; you will be experiencing less distress and inflammation.  When you enter the final 30 days your gut health should be noticeably better with optimal digestion and absorption of nutrients. Many of your SIBO symptoms should be reduced, you should be getting more restful sleep, and your general health should be improved.  After completing the 90-day program many of my patients move into a maintenance program of just using Atrantil® PRO while others feel better continuing with the SIBO Support protocol.

Atrantil® PRO is built on the foundation of the original Atrantil® (that is found in the KBMD Health SIBO Support box) with the addition of spore biotic therapy provided by Bacillus subtillis HU58, Bacillus coagulans SC -208, and Bacillus clausal SC-109.

I recommend this 90-day plan based on my patient’s feedback, our many years of research, and the documented results.  Obviously, you may choose to try one box to see how it works for you before committing to the 3-month program; however, making a 90-day commitment has traditionally been the most effective approach to addressing SIBO symptoms.

Exclusive Offer: Save up to 15%!

** Discount applies to first order only. **


No.  Do Not discontinue use of your prescription medications without prior discussion with your doctor.

We recommend that you start the protocol gently. Use the 1st box as directed to allow your body to recalibrate itself and adjust to the process.  After the first 30 days your body is ready to go into recovery.  At this point take 1 PRO capsule along with your AM packet and 1 PRO capsule along with your PM packet.  At 60 days you should be experiencing significant relief and can now take another PRO along with your AM and PM packets so you will be taking 2 Atrantil® original plus 2 PRO in the AM, and 2 Atrantil® original plus 2 PRO in the PM.

Only you and your doctor can answer that question.  We have customers who continue with the protocol, we have customers who completed the 3-month plan then quit using the box, and we have those who have completed the 3-months and experienced so much improvement that they started a maintenance program of only taking 6 PRO a day; 2 with breakfast, 2 with Lunch, and 2 with dinner, or 3 with breakfast and 3 with dinner.  Different bodies respond differently; each customer can adjust their use to meet their individual needs.

The “use by” date printed on the packets is a 60-day guideline set for prescription pharmaceuticals, not natural supplements, but is required by the packaging company to allow them to package either/or. The ingredients in the KBMD Health SIBO Support Box will remain fresh and effective for an additional 180 days from the “use by” date.

No.  KBMD Health utilizes a pharmaceutical grade facility, the highest quality ingredients, and limits production to individual orders so as to insure a superior product. KBMD Health makes no claims as to the results of any products.  We do not state or imply any guarantees or refunds.

Please address any questions or concerns to: support@kbmdhealth.com